Director
Institute of Genetic Engineering


Prof (Dr.) Amit Chakravarty

5, Ram Mohan Mallick Garden Lane,
Beliaghata, Kolkata 700010, India
e.mail : ige.amit@gmail.com

www. ige-india.com / igmgs-india.com


 

  CURRICULUM VITAE
Date of Birth   17th July, 1947.
 

Highilights of Qualification

DEGREES

 

M. Sc. In Biochemistry (Bombay University)

Ph. D. in Medical Biochemistry (Bombay University)

(From Grant Medical College & J. J. Hospital, Mumbai.)

   
Certified Courses   Medical Genetics (John Hopkins Medical School, USA)

* Molecular Cytogenetics (
Cambridge University)

Molecular Genetics
(Institute of Molecular Medicine, Oxford University, UK)

Plant Tissue Culture
(Pune University.)

Advance course in Assisted Reproductive Technology
(National University Hospital, Singapore)

Prenatal Diagnosis
(European Society Of Genetics Italy)

Obstetric Ultrasound
(Queen Memorial Hospital Glasgow).
   
POST - DOC Traning  

Institute of Molecular Medicine, Oxford (UK).

Dept. of Pathology , Cambridge University, UK

MRC Genetics Unit, Western General Hospital, Edinburgh, UK.

MRC Reproductive Biology Unit, Edinburgh, UK.

Biochemical Genetics Unit, Royal Hospital Sick Children, Edinburg, UK.

Dept. of Obst. & Gynec.Kings College Hospital, Denmark Hill, UK.

IVF (Embryology) - Bourn Hall, Cambridge, UK.

Dept of Obst 7 gynec.,,Baylor College of Medicine , Houston, USA

Reproductive Genetics Institute, Chicago, USA

Clinical & Molecular Genetics Laboratory, College of Medicine ,University of Tennessee, USA

New York Blood Center, New York, USA

CBSC-CryoBank, UCLA, USA.

   
EXPERIENCES IN DIAGNOSTIC AND REASEARCH LABORATORY  

30 yrs. of experiences in Genetic Counseling and Prenatal Diagnosis of Genetic Disorders ( USA / UK /India ) and trained in following areas in Medical Genetics :

  • Clinical Cytogenetics and Molecular Cytogenetics.

  • DNA analysis and PCR based Molecular Diagnosis.

  • Animal and Human Cell Culture.

  • Assisted Reproductive Technology & Cry preservation.

  • Fish Breeding & Genetic Modification.

     
FIELD OF RESEARCH INTEREST  
  • *Molecular Cytogenetics (FISH/ HR-CGH) in Clinical Genetic.

  • Genomic Instability in Cancer

  • Pre-implantation Genetics Diagnosis.

  • Pre-conception Genetic Diagnosis.

  • Stem Cell transplantation in Cancer and Thalassaemia.

  • Gene Therapy and Stem cells Reasearch

  • Genomics of Complex Genetic Disorders ( Diabetes / Cancer)

  • Genomic Instability of Mental Retardation
 
EXPERIENCS  IN TEACHING  

Ex-Reader in Biochemistry at Grant Medical College & Sir J.J. Group of Hospitals Bombay

Teaching program in various Institutions in USA & UK.

PG Teaching & Research .

PG Examiner & Ph.D Thesis Examiner.(Univ. of Mumbai)

Ex-Prof. & Head, Biotechnology Dept, INSTITUTE OF TECHNOLOGY MARINE ENGINEERING, KOLKATA.

 

ASSOCIATION  MEMBERSHIP

 

Board Member, International Society for Prenatal diagnosis

Indian Society for Human Genetics.

Fellow, Indian College of Maternal and Child Health.

Indian Society of Perinatology.

Founder Member & Secretary, Indian Society For Prenatal Diagnosis & Therapy. India

     
PUBLICATIONS :   319  papers (upto year  2009)
     
Published  Books and Contributed chapters in Medical Books.  
  • Human  Cytogenetic  Techniques and  Clinical  application, Bhalani  Publiishing  House, Mumbai ,2000
  • Genetics of  Thalassaemia ; Diagnosis, Management &Prevention ; Thalassaemia Foundation ; 2002
  • Recent Advancement in Obst. & Gynec. ; Dasgupta(ed)
  • Prenatal Diagnosis and Therapy ; Ed itor ; Proceeding of 8th International Conference on Prenatal Diagnosis of  Genetic Disorders ; Jaypee Brothers ; 1998

     * A Chapter in ‘Pregnancy At Risk-Current Concepts’
(Published in 1993)
By Usha Krishna / Shirish Daftary
Chapter :
      *An Introduction To Genetics And Fetal Medicine 
(Published in 1996)
Editor Kamini A. Rao.
Chapters :
1. Genetic Counseling And Multifactorial Inheritance,
2. Laboratory Techniques In Prenatal Diagnosis Of Genetic Disorders.

  • “Role of Genetic Investigations and Counseling

      Test Book of Pediatrics 

(Published in 1991, Re-edition Jan. 1998)
 Editor – Dr. P. M. Udani.
 Editor, Fetal Medicine & surgery ; ISPAT News Letter.

  • Preventive Genetics ; Chapter ; Jaypee ; 2006
     
PAPER PUBLISHED (LAST 10 YRS)  

(1) Sudipa Basu & Amit Chakravarty : Population screening of Thalassaemia – A Preliminary report ; 15th  National Congress of Perinatology ; 3 – 4th April, (1999).

(2) Sudipa Basu and Amit Chakravarty : Thalassaemia trait in our population; BOGS regional annual conference ; Kalyani ; 21st August, (1999).

(3) Sudipa Basu and Amit chakravarty : Thalassaemia Screening  : BOGS Annual Conference, Kolkata ,27th February, (2000).

(4) Sudipa Basu and Amit Chakravarty : Population screening of Thalassaemia in Eastern part of India; 2nd International Conference on Thalassaemia;  New Delhi; (2000).

(5) Amit Chakravarty, Hema Purandarey, Sharad Gogate, Raju Sahetya, Gopal Jaiswal, Pranab Dasgupta, K Ghosh, S Mishra, S Dasgupta. Prenatal diagnosis of genetic disorders – Indian multi-centric experience. ISPD, Barcelona (Spain) (2002)

(6) Amit Chakravarty and Sudipa Basu  :  Thalassaemia Screening in Eastern part of India ; ISPAT Annual Congress ; Pune ; 16th January, (2002).

(7) Sudipa Basu Chakravarty and Amit Chakravarty : Genetic Screening and Prevention of Thalassaemia in Indian population ; ISPD ; Japan ; (2002).

(8) Amit Chakravarty, Hema Purandarey, Sharad Gogate, Raju Sahetya, Gopal Jaiswal, R P Soonawala, Pranab Dasgupta, Sudipa Chakravarty. Prenatal diagnosis of genetic disorders – a multi-centric Indian data. ISPD, Japan (2002)

(9) Jhimli Dasgupta, Udayaditya Sen, Debi Choudhury, Poppy Datta, Abhijit Chakrabarti, Sudipa Basu Chakravarty, Amit Chakravarty and J.K.Dattagupta: Crystallization and Preliminary X-ray structural studies of Haemoglobin A2 and Haemoglobin E, isolated from the blood samples of beta-thalassemic patients;Biochemical Biophysical Research Communications.(2003).


(10) Poppy Datta, Sudipa Basu Chakravarty, Amit Chakravarty and Abhijit Chakrabarti: Interaction of erythroid spectrin with hemoglobin variants: Implications in beta–Thalassemia; Blood Cells, Molecules & Diseases, (2003).

(11) Udayaditya Sen, Jhimli Dasgupta, Debi Choudhury, Poppy Datta,| Abhijit Chakrabarti,| Sudipa Basu Chakrabarty, Amit Chakrabarty,and Jiban K. Dattagupta. Crystal Structures of HbA2 and HbE and Modeling of Hemoglobin  4: Interpretation of the Thermal Stability and the Antisickling Effect of HbA2 and Identification of the Ferrocyanide Binding Site in Hb‡ Biochemistry; (2004).

(12) Poppy Dutta, Sumanta Basu, Sudipa Basu Chakravarty, Amit Chakravarty, Debashish Banerjee, Sharmila Chandra, Abhijit Chakrabarti. Enhanced oxidative cross-linking of hemoglobin E with spectrin and loss of erythrocyte membrane asymmetry in hemoglobin Eb-thalassemia. Blood, Cells and Molecules (2006)

(13) Poppy Dutta, Sudipa Chakravarty, Amit Chakravarty and Abhijit Chakrabarti. Spectrin interactions of globin chains in presence of phosphate metabolites and hydrogen peroxide : Implications in Thalassemia. J of Bioscience. (2007)

(14) Dipankar Bhattacharya, Sutapa Saha, Sumanta Basu, Sudipa Chakravarty , Amit Chakravarty , Debashis Banerjee & Abhijit Chakrabarti. Differential regulation of redox proteins and chaperones in erythrocyte proteomes with varying severity of HbEβ-thalassemia. Blood, Cells & Molecules (accepted for publication) (2009)

15)  Population Screening strategies for Thalssaemia in Eastern India ; Experience of 19,762 cases ; Sudipa Chakravarty, Tridip Chatterjee and Amit Chakravarty ; Institute of Genetic Engineeering, Kolkata ; Birth Defects & Disabilities in The Developing World ; 4th International Conference; New Delhi, India, 4-7 Oct, 2009

16.  Application of HR-CGH in Chromosomal Aberrations ; Amit Chakravarty, Sudipa Chakravarty, Puspal De, Arun Singh ; Institute Of Genetic Medicine and Genomic Science,Kolkara-128 ; Birth Defects & Disabilities in The Developing World ; 4th International Conference; New Delhi, India, 4-7 Oct, 2009


17. Hb-E Beta thalassaemia- wide spectrum of clinical severity in Eastern Inia & Prospective Management ; Sudipa Chakravarty, Tridip Chatterjee, Dipankar bhattacherjee, Sutapa Saha, Sumanta basu, Abhijit Chakraborty, Amit Chakravarty ; Institute of Genetic Engineering, Structural Genomics Divisionn, Saha Institute of Nuclear Physics; Kolkata ; Birth Defects & Disabilities in The Developing World ; 4th International Conference; New Delhi, India, 4-7 Oct, 2009


18. Study of Molecular Background favorable for Hydroxyurea Therapy in Hb-E-beta Thalassaemai patients ; Sudipa Chakravarty, Ritushree Kukreja , Amit Chakravarty, Harpeet Kaur ; Institute of Genetic Engineering , Kolkata ; Functional Genomic unit, Institute Genomics and Integrative Biology, New delhi ; Birth Defects & Disabilities in The Developing World ; 4th International Conference; New Delhi, India, 4-7 Oct, 2009


19. Fetal Chromsomal Anomalies Detected in 10,480  CVS cases ; A Multicentric Prenatal Diagnosis Indian Data ; Amit Chakravarty, Hemat Purandarey, Sudipa Chakravarty ; Institute of Genetc Medicine and Genomic Science, Kolkata; Centre of Genetic Health Care, Mumbai ; Birth Defects & Disabilities in The Developing World ; 4th International Conference; New Delhi, India, 4-7 Oct, 2001


20.Higher HbF Production during Pregnancy may be a cause due to escape of inactivation of “ FCPX( Xp 22.3)  ; Joyita Mukherjee, Kamalesh Roy, Tridip Chatterjee, Amit Chakravarty Sudipa Chakravrty;  Institute of Genetic Engineering, Badu, Kolkata700126;  10th Annual Conference of Indian Society of Prenatal Diagnosis; 3-4th April, 2010 ; Hotel Mariot; Mumbai


21. Herapeutic approach of Resveratrol : A noble HbF Inducer Mimicking the Biological Activity of Hydroxyurea ; Madhuparna Hore*, Tridip Chatterjee*, Anirban Roychowdhury+, Amit Chakravarty+ and Sudipa Chakravarty* ; Institute of Genetic Engineering, Badu, Kolkata700126;  10th Annual Conference of Indian Society of Prenatal Diagnosis; 3-4th April, 2010 ; Hotel Mariot; Mumbai


22. Fetal DNA Analysis for NNAT (Imprinted gene) – a Prenatal diagnostic approach in predicting Pituitary adenoma in the fetus : Bioinformatics approach ; Anindita Ray+, Tridip Chatterjee+,Sudipa Chakravarty+,  Amit Chakravarty* ;; Institute of Genetic Medicine and Genomic Science, Kolkata  ; 10th Annual Conference of Indian Society of Prenatal Diagnosis; 3-4th April, 2010 ; Hotel Mariot; Mumbai

23. Antenatal Screening criteria for Thalassaemia trait (beta and HbE) in pregnant women in Eastern Indian population ; Anirban Roychowdhury*, Tridip Chatterjee+, Amit Chakravarty* and Sudipa Chakravarty^ Institute of Genetic Medicine and Genomic Science badu, Kolkata ; 10th Annual Conference of Indian Society of Prenatal Diagnosis; 3-4th April, 2010 ; Hotel Mariot; Mumbai

24.Dilemmas in Prenatal diagnosis of β-Thalassaemia in Eastern India   ; Amit Chakravarty and Sudipa Chakravarty ; Institute of Genetic Medicine and Genomic Science badu, Kolkata ; 10th Annual Conference of Indian Society of Prenatal Diagnosis; 3-4th April, 2010 ; Hotel Mariot; Mumbai

25. Role of HbE in study of Clinical severity among HbE-β thalassaemia cases – Genomic and Proteomic approach ; Tridip Chatterjee*, Dipankar Bhattacharya#, Sutapa Saha#, Sumanta Basu#, Abhijit Chakrabarti#, Amit Chakravarty*, Sudipa Chakravarty* ; Institute of Genetic Medicine and Genomic Science badu, Kolkata ; 10th Annual Conference of Indian Society of Prenatal Diagnosis; 3-4th April, 2010 ; Hotel Mariot; Mumbai

26.  To study Genomic stability in Mental Retardation by HR-CGH; Amit Chakravarty, *Puspal De, *Sudipa Chakravarty, **Arun Singh  ; Institute of Genetic Medicine and Genomic Science badu, Kolkata ; 10th Annual Conference of Indian Society of Prenatal Diagnosis; 3-4th April, 2010 ; Hotel Mariot; Mumbai

27.  Role Probiotics in Obesity Diagnosis and Management ; Amit Chakravarty and Sudipa Chakravarty; Institute of Genetic Medicine and Genomic Science badu, Kolkata ;34th Annual Conference of Indian Association Medical Microbiologists ;24-28th November,2010 ; Swabhumi, Kolkata

28. Genetic Assessment of Human Embryos ; Amit Chakravarty and Sudipa Chakravarty; Institute of Genetic Medicine and Genomic Science badu, Kolkata ; 16th National Congress of Indian Society for Assisted Reproduction ; 4-6th March, 2011 at Hotel Jaypee Palace; Agra

29. Biology in Silico- Bioinformatics Resources for Health Science Research International  Workshop in collaboration with Health Science Library System, Pittsburgh University (USA)- Amit Chakravarty- Course Coordinator ; 9-10th August, 2011 Institute of Genetic Medicine and Genomic Science Badu, Kolkata

30.Detection of Genomic Imbalances by High Resolution comparative Genomic Hybridization in Neonate witj Multiple Malformation ; Pushpal De, Sudipa Chakravarty, Gorachand Bhattacheriya , Amit Chakravarty ; Institute of Genetic Medicine and Genomic Science Badu, Kolkata and Calcutta National Medical College, Kolkata ; International Conference on  ‘Omics Meet Disease’ and 3rd Annual Meeting of Proteomics- Society (India); December 15-18, 2011 at Saha Institute of Nuclear Physics, Kolkata

31.  Detection of CNVs by HR-CGH and Diagnostic Correlation in Haematological Cancer ;  Somhita Choudhery, Sudipa Chakravarty, Ashok Bhadra and Amit Chakravarty ; Institute of Genetic Medicine and Genomic Science Badu, Kolkata and  Dept of Radio-Diagnosis Bangur Institute of Neuro-Science, Kolkata ; International Conference on  ‘Omics Meet Disease’ and 3rd Annual Meeting  of Proteomics- Society (India); December 15-18, 2011 at Saha Institute of Nuclear Physics, Kolkata

32. Genomics and Proteomics Based case Study of a Thalassaemic Family showing unusual pattern of transfusion requirement ; Tridip Chatterjee, Suchismita Halder,  Amit Chakravarty, Sudipa Chakravarty and Abhijit Chakrabarti ; ; Institute of Genetic Medicine and Genomic Science Badu, Kolkata and  Structural Genomics Division , Saha Institute Nuclear Physics, Kolkata ; International Conference on  ‘Omics Meet Disease’ and of Proteomics- Society (India); December 15-18, 2011 at Saha Institute of Nuclear Physics, Kolkata

33. Genome Wide Analysis for Genetic Instability in Haematological Cancer ; Somhita Choudhery, Sudipa Chakravarty Ashok Bhadra and Amit Chakravarty ; ; Institute of Genetic Medicine and Genomic Science Badu, Kolkata and  Dept of Radio-Diagnosis Bangur Institute of Neuro-Science, Kolkata; 99th  Indian Science Congress ; 3-7th  January, 2012, KIT  University, Bhubaneshwar , Orissaa

34. Evaluation of a new Oral Herbal Iron Chelator Phytic Acid in Thalassaemia ; Anwesha Bhowmick Amit Chakravarty, Tapan Kr Chatterjee and Sudipa Chakravarty ; Institute of Genetic Engineerin, Badu, Kolkata and Dept of Pharmaceutical Technology Jadavpur University, Kolkata ;  99th  Indian Science Congress ; 3-7th  January, 2012, KIT  University, Bhubaneshwar , Orissaa

35. Altered Hb Switching in Beta and Hb E- beta thalassaemia pattern ; Tridip Chatterjee Amit Chakravarty Sudipa Chakravarty ; Institute of Genetic Medicine and Genomic Science Badu, Kolkata; 99th  Indian Science Congress ; 3-7th  January, 2012, KIT  University, Bhubaneshwar , Orissaa

     
ACHIEVEMENTS
 

Established First Private Genetic Diagnostic Centre at Bombay India In 1981.

Established 2 other Private Genetic Diagnostic Centre in India (Pune & Calcutta)

Conducted Workshops Thro’ INDIAN SOCIETY OF PRENATAL DIAGNOSIS INDIA in Different States in India

Awarded Fellowship, Indian College of Maternal and Child Health.

Founder Trustee of ‘Biotech Foundation’ & established “Institute of Genetic Engineering”.and Institute of Genetic Medicine and Genomic Science, at Kolkata

Organising Secretary ; International Conference of International Society for Prenatal Diagnosis (ISPD) ; Goa;1996

Trained More Than 50 Medical Doctors & Scientists in Human Cytogenetics & Molecular Genetics.

     
REFERENCES
 
  1. Prof. Joe .L. Simpson.  Dept. Obst. &  Gynec. , Baylor  College  Medicine , Houston , USA
  2. Dr John Old, Intitute of Molecular Medicine,Oxford University
  3. Dr Avirachan  Tharapel , Clinical & Molecular  Genetics , Dept. of  Pediatrics, University  of  Tenessee, USA
  4. Prof. M.Ferguson Smith, Dept. of  Pathology, University  of  Cambridge, UK
  5. Prof. Charles  Rodeck , Dept. Obst. & Gynec, UCL, London, UK
  1. Dr Subir Dutta , Senior Consultant Pathologist, Kolkata
  2. Dr B.N.Chakraborty, Director,Institute of Reproductive Medicine, Salt Lake, Kolkata
  3. Dr Manish Chakraborty, Ex-Director; Institute of Tropical Medicne; Kolkata
     
PRESENT POSITION
 

Director ,Institute of Genetic Engineering, Kolkata-700128

Director , Institute of Genetic Medicine and Genomic Science, Kolkata - 700128

     
MAILING  ADDRESS
 

Resident  Address :  PURBAGANA , 5 RAM MOHAN MALLICK GARDEN LANE , BELIAGHATA, KOLKATA-10

Tel : 2371 2972  ; M ( 93310 34762) 
e.mail :   ige.amit@gmail.com